Slowing the aging process is relative to your age. When we are young we really don’t think about it. But once we hit the age of 35, and our bodies begin to decline in their health, the idea of slowing the aging process begins to enter our thoughts.
For many, once they reach the age of 60 they really begin to look for ways to help extend their life with good health.
There is a class of compounds called senolytics that have been used in experimental models to improve health and extend the lifespan.
One new compound that has shown great promise is fisetin. This is a flavonoid found in various fruits and vegetables like strawberries, apples, grapes, and onions.
In animal studies, fisetin has extending lifespan by approximately 10 percent.
Senolytic compounds like fisetin help your body clear away old and damaged cells to make room for new and healthy cells.
This removal of old and damaged cells is critical to your overall health because:
They cause damage to surrounding tissue by creating harmful compounds that lead to chronic inflammation.
As I’ve discussed in other articles, chronic inflammation is the root cause of almost all diseases.
Senolytics are polyphenol compounds that can destroy these old and damaged cells.
One such polyphenol compound is quercetin.
But new research shows that fisetin is much more effective in eliminated old and damaged cells. In a recent study published in the journal Aging, fisetin helped to eliminate approximately 70% of old and damaged cells. Equally important, it did no damage to normal, healthy human cells.
When given to mice who had the human equivalent of 75 years of age, fisetin extended their lifespan by about 10 percent.
In addition to slowing the aging process, this flavonoid can also provide the following benefits:
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As an antioxidant to protect your cells from free radical damage.
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As an anti-inflammatory compound that helps to reduce the production of pro-inflammatory compounds.
There is ongoing research on how this ingredient can also provide benefits in the following areas:
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Reduce heart damage from a heart attack.
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Help to control several aggressive cancers (brain cancer and breast cancer).
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Extends the window for treating stroke patients with drugs that dissolve or remove blood clots from 3 hours to 5 hours.
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May help to prevent obesity and other metabolic disorders like type II diabetes.
Now the downside to the use of fisetin has been how quickly it’s metabolized in the digestive tract. This means that only a small amount of this flavonoid gets into your blood stream.
Scientists have been working to overcome this challenge. Recent studies have shown that when combined with a natural fiber from the spice fenugreek you can increase the bio-availability of fisetin by as much as 25 times.
This allows more of this flavonoid to circulate throughout your body, which may promote better health and longevity. Thus, slowing the aging process even for older adults.
Blessing Lives Through Nitric Oxide Therapy!
Dan Hammer
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